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Photobiomodulation—Underlying Mechanism and Clinical Applications

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excerpts of the thesis:

 

Abstract
The purpose of this study is to explore the possibilities for the application of laser therapy in medicine and dentistry by analyzing lasers’ underlying mechanism of action on different cells, with a special focus on stem cells and mechanisms of repair

 

 

Introduction

The effect of PBM in accelerating the healing process was introduced in the 1960s by Endre Mester and National Aeronautics and Space Administration (NASA) researchers used it for enhancing the healing processes in space Laser and LED light induce a photobiomodulation (PBM) effect which is used to accelerate healing, as it increases cell viability by stimulating the mitochondrial and cell membrane photoreceptors synthesis of ATP.

 

...Mitochondria contain chromophores which absorb photons from PBM.......

 

 

Tissue Regeneration after Laser Treatment

 

 

Types of Lasers and Their Application in Medicine

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The photobiomodulatory effect induced mainly by the diode lasers with wavelengths in the red and near-infrared range (630–940 nm) affects a modulation of cell proliferation. The use of lasers with wavelengths from an “optical window” (600–1100 nm) result in deeper penetration and therefore evokes a wider cell-light response.

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